diff --git a/Benchmark-Models/Isensee_JCB2018/model_Isensee_JCB2018.xml b/Benchmark-Models/Isensee_JCB2018/model_Isensee_JCB2018.xml
index 4b5721f..66d7847 100644
--- a/Benchmark-Models/Isensee_JCB2018/model_Isensee_JCB2018.xml
+++ b/Benchmark-Models/Isensee_JCB2018/model_Isensee_JCB2018.xml
@@ -149,19 +149,19 @@
       <parameter metaid="fourABnOH_level" id="fourABnOH_level" value="0" units="substance"/>
       <parameter metaid="fourABnOH_time" id="fourABnOH_incubation_time" value="0" units="time"/>
       <!-- H1: different KD -->
-      <parameter metaid="xi_KD_Rp8_Br_cAMPS"      id="xi_KD_Rp8_Br_cAMPS"      value="0"/>
-      <parameter metaid="xi_KD_Rp8_pCPT_cAMPS"    id="xi_KD_Rp8_pCPT_cAMPS"    value="0"/>
-      <parameter metaid="xi_KD_Rp_cAMPS"          id="xi_KD_Rp_cAMPS"          value="0"/>
-      <parameter metaid="xi_KD_Sp8_Br_cAMPS"      id="xi_KD_Sp8_Br_cAMPS"      value="0"/>
+      <parameter metaid="xi_KD_Rp8_Br_cAMPS"      id="xi_KD_Rp8_Br_cAMPS"      value="1"/>
+      <parameter metaid="xi_KD_Rp8_pCPT_cAMPS"    id="xi_KD_Rp8_pCPT_cAMPS"    value="1"/>
+      <parameter metaid="xi_KD_Rp_cAMPS"          id="xi_KD_Rp_cAMPS"          value="1"/>
+      <parameter metaid="xi_KD_Sp8_Br_cAMPS"      id="xi_KD_Sp8_Br_cAMPS"      value="1"/>
       <!-- H2: AC inhibition -->
       <parameter metaid="xi_pAC"                  id="xi_pAC"                  value="0"/>
       <parameter metaid="kp_AC"                   id="kp_AC"                   value="0"/>
       <parameter metaid="kdp_AC"                  id="kdp_AC"                  value="0"/>
       <!-- H3: incomplete import -->
-      <parameter metaid="xi_i_Rp8_Br_cAMPS_pAB"   id="xi_i_Rp8_Br_cAMPS_pAB"   value="0"/>
-      <parameter metaid="xi_i_Rp8_pCPT_cAMPS_pAB" id="xi_i_Rp8_pCPT_cAMPS_pAB" value="0"/>
-      <parameter metaid="xi_i_Rp_cAMPS_pAB"       id="xi_i_Rp_cAMPS_pAB"       value="0"/>
-      <parameter metaid="xi_i_Sp8_Br_cAMPS_AM"    id="xi_i_Sp8_Br_cAMPS_AM"    value="0"/>
+      <parameter metaid="xi_i_Rp8_Br_cAMPS_pAB"   id="xi_i_Rp8_Br_cAMPS_pAB"   value="1"/>
+      <parameter metaid="xi_i_Rp8_pCPT_cAMPS_pAB" id="xi_i_Rp8_pCPT_cAMPS_pAB" value="1"/>
+      <parameter metaid="xi_i_Rp_cAMPS_pAB"       id="xi_i_Rp_cAMPS_pAB"       value="1"/>
+      <parameter metaid="xi_i_Sp8_Br_cAMPS_AM"    id="xi_i_Sp8_Br_cAMPS_AM"    value="1"/>
       <!-- H4: PDE inhibition -->
       <parameter metaid="xi_pPDE"                 id="xi_pPDE"                 value="0"/>
       <parameter metaid="kf_PDE_Csub"             id="kf_PDE_Csub"             value="0"/>