diff --git a/pyproject.toml b/pyproject.toml
index 722996cf..68a11bbc 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -52,6 +52,7 @@ dependencies = [
     "pillow >= 7.0.0",
     "pywinauto >= 0.6.8; sys_platform == 'windows'",
     "pyyaml >= 5.3",
+    "requests >= 2.0.0",
     "scikit-image >= 0.17.1",
     "scipy >= 1.3.2",
     "tifffile >= 2019.7.26.2",
diff --git a/readme.md b/readme.md
index 614d8dce..e152a481 100644
--- a/readme.md
+++ b/readme.md
@@ -21,6 +21,7 @@ Cameras supported:
 
 - ASI Timepix
 - ASI CheeTah through `serval-toolkit` library
+- DECTRIS cameras through SIMPLON API
 - TVIPS cameras through EMMENU4 API
 - Quantum Detectors MerlinEM
 - Gatan cameras through FEI scripting interface
diff --git a/requirements.txt b/requirements.txt
index e338809c..651dce59 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -10,6 +10,7 @@ pandas >= 1.0.0
 pillow >= 7.0.0
 pywinauto >= 0.6.8; sys_platform == 'windows'
 pyyaml >= 5.3
+requests >= 2.0.0
 scikit-image >= 0.17.1
 scipy >= 1.3.2
 tifffile >= 2019.7.26.2
diff --git a/src/instamatic/camera/camera.py b/src/instamatic/camera/camera.py
index 4deba61f..f64a5ab0 100644
--- a/src/instamatic/camera/camera.py
+++ b/src/instamatic/camera/camera.py
@@ -33,6 +33,8 @@ def get_camera_class(interface: str) -> type[CameraBase]:
         from instamatic.camera.camera_emmenu import CameraEMMENU as cam
     elif interface == 'serval':
         from instamatic.camera.camera_serval import CameraServal as cam
+    elif interface == 'simplon':
+        from instamatic.camera.camera_simplon import CameraSimplon as cam
     elif interface == 'merlin':
         from instamatic.camera.camera_merlin import CameraMerlin as cam
     else:
diff --git a/src/instamatic/camera/camera_simplon.py b/src/instamatic/camera/camera_simplon.py
new file mode 100644
index 00000000..dcbb4de9
--- /dev/null
+++ b/src/instamatic/camera/camera_simplon.py
@@ -0,0 +1,180 @@
+from __future__ import annotations
+
+import atexit
+import logging
+import time
+from concurrent.futures import ThreadPoolExecutor
+from io import BytesIO
+from json.decoder import JSONDecodeError
+from typing import Any, Generator, Optional, Tuple
+
+import numpy as np
+import requests
+import tifffile
+
+from instamatic.camera.camera_base import CameraBase
+
+logger = logging.getLogger(__name__)
+
+
+class CameraSimplon(CameraBase):
+    """Interfaces with Dectris detectors via the SIMPLON REST-like API."""
+
+    streamable = True
+    MIN_EXPOSURE = 0.0001
+    MAX_EXPOSURE = 60.0
+    BAD_EXPOSURE_MSG = 'Requested exposure is out of supported range (>0-1m)'
+
+    def __init__(self, name='dectris') -> None:
+        """Initialize camera module, vars, establish connection & cleanup."""
+        super().__init__(name)
+
+        self.base_url = getattr(self, 'url', 'http://localhost:8000/')
+        self.api_version = getattr(self, 'api_version', '1.8.0')
+
+        self.establish_connection()
+        logger.info(f'Camera {self.get_name()} initialized via SIMPLON API')
+
+        te_name = 'simplon-trigger'
+        self._te = ThreadPoolExecutor(max_workers=1, thread_name_prefix=te_name)
+        atexit.register(self.release_connection)
+
+    def _request_url(self, module: str, *params: str, timeout: int = 0) -> str:
+        """Construct the SIMPLON API REST URL from params (and timeout)."""
+        base = self.base_url.rstrip('/')
+        url = f'{base}/{module}/api/{self.api_version}/' + '/'.join(params)
+        url += f'?timeout={int(timeout)}' if timeout else ''
+        return url
+
+    def _wait4idle(self, timeout=5.0):
+        """Wait until the camera is idle, or raise if timeout reached."""
+        t0 = time.time()
+        while self.get('detector', 'status', 'state') != 'idle':
+            if time.time() - t0 > timeout:
+                m = 'Detector not idle - another client may be controlling it'
+                raise RuntimeError(m)
+            time.sleep(0.1)
+
+    def get(self, module: str, *params: str, timeout: int = 0) -> Any:
+        """Perform a GET request on a SIMPLON parameter resource."""
+        url = self._request_url(module, *params, timeout=timeout)
+        r = requests.get(url)
+        r.raise_for_status()
+        return r.json().get('value')
+
+    def put(self, module: str, *params: str, timeout: int = 0, value=None) -> dict:
+        """Perform a PUT request to configure a SIMPLON parameter resource."""
+        url = self._request_url(module, *params, timeout=timeout)
+        r = requests.put(url, json={} if value is None else {'value': value})
+        r.raise_for_status()
+        try:
+            return r.json()
+        except JSONDecodeError:
+            return {}
+
+    def establish_connection(self) -> None:
+        """Establish connection, initialize detector, apply initial config."""
+        logger.info(f'Connecting to SIMPLON detector at {self.base_url}')
+
+        try:
+            self.put('detector', 'command', 'initialize')
+        except Exception as e:
+            logger.warning(f'Initialization failed or already initialized: {e}')
+
+        self.put('monitor', 'config', 'mode', value='enabled')
+        self.put('monitor', 'config', 'buffer_size', value=100)
+        self.put('monitor', 'config', 'discard_new', value=False)
+        self.put('detector', 'config', 'trigger_mode', value='ints')
+
+        detector_config = getattr(self, 'detector_config', {})
+        for key, value in detector_config.items():
+            try:
+                self.put('detector', 'config', key, value=value)
+                logger.debug(f'Set detector config {key} = {value}')
+            except Exception as e:
+                logger.error(f'Failed to set detector config {key} = {value}: {e}')
+
+    def release_connection(self) -> None:
+        """Release connection, disarm the detector, disable the monitor."""
+        try:
+            self.put('detector', 'command', 'disarm')
+        except Exception:
+            pass
+        try:
+            self.put('monitor', 'config', 'mode', value='disabled')
+        except Exception:
+            pass
+        self._te.shutdown(wait=False)
+        logger.info(f"Connection to camera '{self.get_name()}' released")
+
+    def get_image(self, exposure: Optional[float] = None, **kwargs) -> np.ndarray:
+        """Acquire a single image with specified exposure time via monitor."""
+        return list(self.get_movie(1, exposure=exposure))[0]
+
+    def get_movie(
+        self,
+        n_frames: int = 1,
+        exposure: Optional[float] = None,
+        **kwargs: Any,
+    ) -> Generator[np.ndarray]:
+        """Eagerly configure, lazily yield `n_frames` with `exposure`."""
+        e = self.default_exposure if exposure is None else exposure
+
+        if e < self.MIN_EXPOSURE or e > self.MAX_EXPOSURE:
+            raise ValueError(f'{self.BAD_EXPOSURE_MSG}: {e}s')
+        logger.debug(f'Collecting {n_frames} images with exposure {e} s')
+
+        self._wait4idle()
+        self.put('detector', 'config', 'count_time', value=e)
+        self.put('detector', 'config', 'nimages', value=n_frames)
+
+        try:
+            self.put('monitor', 'command', 'clear')
+        except Exception:
+            pass
+
+        self.put('detector', 'command', 'arm')
+        timeout = int(1000 * (e * 2 + 1))  # s -> ms
+        url = self._request_url('monitor', 'images', 'next', timeout=timeout)
+
+        def _get_movie_inner(_n: int) -> Generator[np.ndarray]:
+            """This data collection is executed lazily i.e. when iterating."""
+            t_future = self._te.submit(self.put, 'detector', 'command', 'trigger')
+            try:
+                for i in range(_n):
+                    r = requests.get(url, headers={'Accept': 'image/tiff'})
+                    if r.status_code == 408:
+                        msg = f'No frame {i}/{_n} received within {timeout}ms'
+                        raise TimeoutError(msg)
+                    r.raise_for_status()
+                    yield tifffile.imread(BytesIO(r.content))
+                t_future.result()  # propagate any late exception, join thread
+            except Exception:
+                try:
+                    self.put('detector', 'command', 'abort')
+                except Exception as exc:
+                    logger.error(f'Error aborting after failed movie: {exc}')
+                if not t_future.done():
+                    try:
+                        t_future.result(timeout=_n * timeout / 1000)
+                    except Exception as exc:
+                        logger.warning(f'Trigger did not return after abort: {exc}')
+                raise
+
+        return _get_movie_inner(n_frames)
+
+    def get_image_dimensions(self) -> Tuple[int, int]:
+        """Get the binned dimensions reported by the camera."""
+        binning = self.get_binning()
+        try:
+            dim_x = int(self.get('detector', 'config', 'x_pixels_in_detector'))
+            dim_y = int(self.get('detector', 'config', 'y_pixels_in_detector'))
+        except Exception:
+            dim_x, dim_y = self.get_camera_dimensions()
+        return int(dim_x / binning), int(dim_y / binning)
+
+
+if __name__ == '__main__':
+    logging.basicConfig(level=logging.INFO)
+    cam = CameraSimplon()
+    print('SIMPLON camera initialized successfully.')
diff --git a/src/instamatic/config/camera/simplon.yaml b/src/instamatic/config/camera/simplon.yaml
new file mode 100644
index 00000000..25aa269d
--- /dev/null
+++ b/src/instamatic/config/camera/simplon.yaml
@@ -0,0 +1,25 @@
+camera_rotation_vs_stage_xy: 0.0
+default_binsize: 1
+default_exposure: 0.05
+
+dimensions: [512, 512]  # example dimensions for QUADRO
+
+calib_beamshift:
+  gridsize: 5
+  stepsize: 2000
+  delay: 0.1
+
+dynamic_range: 11800
+interface: simplon
+physical_pixelsize: 0.075  # pixel size in mm for QUADRO
+possible_binsizes: [1]
+
+stretch_amplitude: 0.0
+stretch_azimuth: 0.0
+
+url: 'http://localhost:8080'
+api_version: '1.8.0'
+
+detector_config:
+  trigger_mode: 'ints'
+  photon_energy: 200000.0